SYRE SPYRE THERAPEUTICS INC
Health Care · Russell 2000
Next earnings: not announced yet
What 21 analyst firms say about SPYRE THERAPEUTICS INC: their latest ratings, price targets and how far the stock is from them. How it works
Analyst window: Latest analyst report within last 1 year
Analyst view · last 1Y
20 rated views · 22 analyst/firm records · 21 firms
Radar score
Recent analyst activity · last 90 days
Our tracked history has 17 reports on SYRE from 10 analyst firms in the last 90 days (21 firms in the past year).
Comparing each firm's latest target with its previous one: 3 raised their price target, 3 lowered it, 2 left it unchanged and 1 has its first observed target in the past year.
No firm's latest available rating differs from its previous one.
Latest observed target change: Guggenheim raised its target from $130.00 (set 5 Aug 2026) to $135.00 on 4 Nov 2026.
Last 1 year. Latest opinion per identifiable analyst within the last 1 year. BUY / HOLD / SELL each count one current analyst vote; unnamed firm records are a fallback.
| Firm | Analyst | Latest rating | Report date | Latest target (USD) |
|---|---|---|---|---|
| Baird | Brian P Skorney | Buy | 17 Aug 2026 | 116.00 USD |
| Baird | Colleen Kusy | — | 5 Aug 2026 | 120.00 USD |
| BTIG | Julian Harrison | Buy | 19 Oct 2026 | 121.00 USD |
| Citigroup | Samantha Semenkow | Buy | 6 May 2026 | 97.00 USD |
| Deutsche Bank | David Hoang | Buy | 26 Aug 2026 | 127.00 USD |
| Evercore ISI | Umer Raffat | Buy | 1 Jul 2026 | — |
| Guggenheim | Yastin Suneja | Buy | 5 Aug 2026 | 130.00 USD |
| Jefferies | Akash Tewari | Buy | 1 Oct 2026 | 129.00 USD |
| Jonestrading | Debanjana Chatterjee | Buy | 12 Aug 2026 | 130.00 USD |
| JPMorgan | Hardik Parikh | Buy | 1 Oct 2026 | 110.00 USD |
| Leerink Partners | Thomas J Smith | Buy | 4 Aug 2026 | 128.00 USD |
| Lifesci Capital | Sam Slutsky | Buy | 9 Jul 2026 | 119.00 USD |
| Mizuho | Joseph Catanzaro | Buy | 13 Jul 2026 | 120.00 USD |
| Raymond James | Martin Auster | Buy | 4 Aug 2026 | 80.00 USD · 13 Apr 2026 |
| Stifel | Alex Thompson | Buy | 6 May 2026 | 107.00 USD |
| TD Cowen | Tyler Van Buren | Buy | 17 Feb 2026 | — |
| UBS | Alice Nettleton | Buy | 11 Oct 2026 | 120.00 USD |
| Wedbush | David Nierengarten | Buy | 9 Sep 2026 | 123.00 USD |
| Weiss Ratings | Unnamed analyst | — | 1 Sep 2026 | — |
| Wells Fargo | Yanan Zhu | Buy | 5 Aug 2026 | 115.00 USD |
| Wolfe Research | Andy Chen | Hold | 28 Jul 2026 | — |
| Data feed RESEARCH | Research Team | Hold | 15 Jun 2026 | Conflicting reports · excluded |
Partial coverage · checked 6 Nov (6 Nov 2026, 04:07 ET). Some research records could not be refreshed. Cached records retained. Prices stream live during the US session; otherwise stored prices delayed about 15 minutes. A summary of analyst opinion, not investment advice.